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Download the short program  here;
and the complete program (including abstracts)  here.

Connect to the WebApp for the GSCN Conference 2022  Link.

Main Hall (MH); Red Hall (RH); White Hall front (WHf); White Hall rear (WHr); Gallery (GA)

Tuesday Wednesday Thursday Friday

Tuesday, 13 September 2022

14:00 - 14:30
GSCN Conference 2022
14:00 - 14:10 Welcome to Münster and to Halle Münsterland
Angela Stähler, Major of Münster
14:10 - 14:25 Greeting from the BMBF
Representative, Federal Ministry of Education and Research (BMBF)
14:25 - 14:30 Opening of GSCN Conference 2022
Hans Schöler, President GSCN
14:30 - 15:15
Keynote lecture I                                                          supported by Sartorius
K1 - Stem cells in the adult brain: regulation and diversity
Fiona Doetsch, Biocenter Basel, Switzerland
Chair: Heiko Lickert
15:15 - 16:00
Keynote lecture II
K2 - Decoding the mechanisms governing human hematopoietic stem cell specification and self-renewal
Hanna Mikkola, University of California, Los Angeles, USA
Chair: Claudia Waskow
16:00 - 16:30 Break time / Industry exhibition
16:30 - 18:30
Poster session I (Poster number P001-P091, X01)  supported by Stem Genomics
(with beverages)
Stem cells in regenerative therapies: P001 - P027
Somatic stem cells & development: P028 - P034
Pluripotency & reprograming: P035 - P056
Organoids: new models for diseases: P057 - P091

Even numbers: 16:30 - 17:30
Odd numbers: 17:30 - 18:30
  Evening at leisure


Wednesday, 14 September 2022

09:00 - 10:30 Concurrent scientific working group session I
09:00 - 10:30
Organoids: new models for diseases                         supported by Takara
(Chairs: Sina Bartfeld / Heiko Lickert)
09:00 - 09:30 T01 - Human gastric organoids reveal Helicobacter pylori tropism to differentiated pit cells dependent on chemotaxis
Sina Bartfeld, TU Berlin
09:30 - 09:45 T02 - A compartimentalized assembloid model of the optic nerve
Kevin Achberger, Uni Tübingen
09:45 - 10:00 T03 - SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids
Yotam Menuchin-Lasowski, MPI for Molecular Biomedicine, Münster
10:00 - 10:15 T04 - Human hematopoietic liver organoids as model platform of multi-lineage hepatogenesis and complex hepatitis
Milad Rezvani, Charité Berlin
10:15 - 10:30 T05 - Deep learning for high-throughput microscopy image analysis of organoids
Dominik Waibel, Helmholtz Zentrum Munich
09:00 - 10:30
Stem cells in regenerative therapies
(Chairs: Ulrich Martin / Wolfgang Wagner)
09:00 - 09:30 T06 - IDUNN trial – mesenchymal stromal cells (MSC) “MC0518” for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGvHD)
Lisa-Marie Pfeffermann, DRK Blood Donor Service, Frankfurt
09:30 - 09:45 T07 - Continuous production of hiPSC-derived natural killer cells and dendritic cells using a concurrent differentiation platform
Fawaz Saleh, Hannover Medical School (MHH)
09:45 - 10:00 T08 - Mesenchymal stromal cell-derived extracellular: Immunomodulatory and pro-regenerative drugs of the future?
Bernd Giebel, University hospital Essen
10:00 - 10:15 T09 - Contribution of human stem cell-derived cardiomyocytes subtypes to bioartificial cardiac tissue formation and function
Veronika Fricke, Hannover Medical School (MHH)
10:15 - 10:30 T10 - Microglia cell therapy to treat CNS manifestations in lysosomal storage diseases
Christoph Patsch, BlueRock Therapeutics, Heidelberg
09:00 - 10:30
Stem cells in aging & disease                             supported by biotechne
(Chairs: Hartmut Geiger / Andreas Trumpp)
09:00 - 09:30 T11 - Dormancy, diapause and senescence in stem cells and cancer
Andreas Trumpp, DKFZ Heidelberg
09:30 - 09:45 T12 - Cellular age is accelerated in myeloproliferative neoplasms
Vithurithra Tharmapalan, University hospital RWTH Aachen
09:45 - 10:00 T13 - Single-cell multi-omics unveils transcriptional regulation of the hematopoietic response to sepsis
Alessandro Greco, DKFZ Heidelberg
10:00 - 10:15 T14 - Immunomodulation by resident neural stem cells suppresses chronic inflammation
Yu-Hsuan Chu, University Freiburg
10:15 - 10:30 T15 - Interferon regulates stem cell function at all ages by orchestrating mTOR and cell cycle
Damian Carvajal Ibanez, DKFZ Heidelberg
10:30 - 11:00 Break time / Industry exhibition                                  supported by Peprotech
11:00 - 12:00
GSCN General Membership Meeting
Executive Board & Managing Director
Hans Schöler, Claudia Waskow, Hartmut Geiger, Michael Cross, Andreas Trumpp, Daniel Besser
12:00 - 13:30 Lunch break / Industry exhibition                                  supported by Evotec
13:30 - 18:05
20 Years Stem Cell Network NRW Anniversary Symposium
Chair: Oliver Brüstle
13:30 - 13:40
Welcome to the Anniversary Symposium
Oliver Brüstle, Institute of Reconstructive Neurobiology, University of Bonn
13:40 - 13:50
Welcome from the Ministry of Culture and Science of North Rhine-Westphalia
13:50 - 14:35
Keynote lecture
NRW01 - Stem cell technologies for the study of Huntingtin structure-function relationship and striatal neurons development and pathogenesis at single-cell resolution
Elena Cattaneo, National Institute of Molecular Genetics, Milan, Italy
14:35 - 14:40 Short break
14:40 - 16:00
NRW scientific session I
(Chairs: Peter Horn / Martin Zenke)
14:40 - 15:05 NRW02 - Cerebral organoids to  model developmental brain pathologies in vitro
Julia Ladewig, Hector Institute for Translational Brain Research (HITBR) Central Institute of Mental Health, University of Heidelberg
15:05 - 15:30 NRW03 - Epigenetic biomarkers to track differentiation of pluripotent stem cells
Wolfgang Wagner, Institute for Stem Cell Biology, Aachen University Medical School
15:30 - 15:45 NRW04Cell-cell communication promotes extraembryonic lineage differentiation in embryo-like stem cell aggregates
Christian Schröter, MPI for Molecular Physiology, Dortmund
15:45 - 16:00 NRW05 - Human forebrain brain organoids assembling bilateral eye primordia
Jay Gopalakrishnan, Heinrich Heine University, Düsseldorf 
16:00 - 16:30 Break time / Industry exhibition
16:30 - 18:05
NRW scientific session II
(Chairs: Andreas Faissner / Edda Tobiasch)
16:30 - 16:55 NRW06 - Ribosomes are decision hubs for early embryonic cell fate decisions
Leo Kurian, University of Cologne
16:55 - 17:20 NRW07 - Multicellular coordination in context
Takashi Hiiragi, Hubrecht Institute Utrecht, The Netherlands
17:20 - 17:35 NRW08 - Epigenetic and transcriptomic changes during blood-to-neural stem cell conversion: Transcription factor-induced de-aging?
Lea Jessica Flitsch, University of Bonn
17:35 - 17:50 NRW09 - Enteroviruses modulate the cellular HCN4 channel trafficking and alter electrochemical signal generation in hiPSC-derived pacemaker-like cells
Stefan Peischard, University Hospital Münster
17:50 - 18:05 NRW10 - Reprograming-driven drug discovery identifies an efficacious repurposing candidate for the treatment of Leigh syndrome patients
Annika Zink, Heinrich Heine University, Düsseldorf
18:05 - 18:30 Break time / Industry exhibition
18:30 - 19:15
Keynote lecture III (ELSA)
K3 - Risk ethics and the future of genome editing
Dieter Birnbacher, Heinrich Heine University, Düsseldorf
Chair: Tobias Cantz
19:15 - 21:00 GSCN Get-together for all participants
Dinner buffet in the Foyer

Thursday, 15 September 2022

09:00 - 10:30 Concurrent scientific working group session II
09:00 - 10:30
Stem cell in disease modeling & drug development I
(Chairs: Oliver Brüstle / Bert Klebl)
09:00 - 09:30 T16 - Exploring the role of FOXF2 in small vessel disease (SVD) in a human iPSC-derived model of the neurovascular unit (NVU)
Dominik Paquet, LMU/DZNE Munich
09:30 - 09:45 T17 - Assessing developmental neurotoxicity of paracetamol using human neural progenitor cells and cortical spheroids
Mohamad Hajo, University of Bonn
09:45 - 10:00 T18 - Patient-derived stem cells to study the pathology of autism spectrum disorders-related voltage-gated calcium channel gain-of-function mutations
Marcel Tisch, University of Innsbruck
10:00 - 10:15 T19 - hiPSC-derived adrenocortical cell model reveals the pathophysiology of KCNJ5 mutation in primary aldosteronism
Kieu Nhi Tran Vo, Charité/BIH, Berlin
10:15 - 10:30 T20 - Novel tools for enhancing stem cell-based modeling of pain disorders
Pascal Röderer, University of Bonn
09:00 - 10:30
Hematopoietic stem cells
(Chairs: Michael Rieger / Claudia Waskow)
09:00 - 09:30 T21 - Somatic mutations in hematopoietic stem cells: competitive advantage and organ interplay in clonal hematopoiesis
Michael Rieger, Goethe University, Frankfurt a.M.
09:30 - 09:45 T22 - Hematopoietic progenitors drive human macrophage ontogeny from pluripotent stem cells
Nico Lachmann, Hannover Medical School (MHH)
09:45 - 10:00 T23 - Aged or trained – hematopoietic stem and progenitor cells after recovery from respiratory infection
Marcel G.E. Rommel, Paul-Ehrlich-Institute, Langen
10:00 - 10:15 T24 - The response of the murine niche to donor human HSC in NSGW41 mice
Nina Henning, Leibniz Institute on Aging (FLI), Jena
10:15 - 10:30 T25 - Long-term ex vivo hematopoietic stem cell (HSC) expansion using novel bone-lining reinvigorating mesenchymal stromal cells (rMSCs)
Shubhankar Sood, DKFZ Heidelberg
09:00 - 10:30
Somatic stem cells & development
(Chairs: Thomas Braun / Ana Martin-Villalba)
09:00 - 09:30 T26 - Targeting RNA modifications in disease
Michaela Frye, DKFZ Heidelberg
09:30 - 09:45 T27 - Transition-state, branch-point associated cells give rise to the majority of ciliated cells in the mouse lung
Keynoosh Khalooghi, MPI for Heart and Lung Research, Bad Nauheim
09:45 - 10:00 T28 - Chemical hPSC cardiac progenitor’s stabilization in vitro reflects stage-specific heart development in vivo
Emiliano Bolesani, Hannover Medical School (MHH)
10:00 - 10:15 T29 - Embryonic progenitors undergo a behavioral change on the way to becoming adult stem cells in the medaka retina
Natalia Sokolova, COS University Heidelberg
10:15 - 10:30 T30 - Stem cell niche formation induces stereotypical organogenesis in Drosophila ovary
Ana-Maria Zamfirescu, Hannover Medical School (MHH)
09:00 - 12:30
Gallery 2
ELSA Symposium
Ethical discussions on early embryonic entities, gender classifications and genome editing
Organizers: Aljoscha Berve / Tobias Cantz
10:30 - 11:00 Break time / Industry exhibition                            supported by Synthego​
11:00 - 12:30 Industry session: "Technologies from GSCN industry partners"
11:00 - 12:30
Gold & Silver Supporter
(Chairs: Michael Cross / Sira Groscurth)
11:00 - 11:30 C01 - Advancements in modeling disease efficiently
Karthi Rajamani​, Takara Bio Europe, SAS
11:30 - 12:00 C02 - CellCelector - automated clonal colony picking and single cell cloning for stem cell applications
Jens Eberhardt, Sartorius
12:00 - 12:30 C03 - Advanced hPSC bioprocessing in stirred tank bioreactors
Robert Zweigerdt, Hannover Medical School (MHH) for Eppendorf SE
11:00 - 12:30
Silver Supporter
(Chairs: Hannes Klump / Richard Schäfer)
11:00 - 11:30 C04 - Boost your stem cell culture workflow with Bio-Techne
Simon Sumer, bio-techne
11:30 - 12:00 C05 - Robust workflows for the expansion of pluripotent stem cells in 3D suspension culture
Camille Lemey, STEMCELL Technologies
12:00 - 12:30 C06 - High-Content, high-throughput imaging and analysis of intestinal organoid arrays
Robert Storm, Molecular Devices GmbH
11:00 - 12:30
Bronze Supporter I
(Chairs: Sebastian Diecke / Ingo Roeder)
11:00 - 11:15 C07 - A revolutionary benchtop platform improving viability, yield and long-term culture of
3D cell models
Amir Keric, OLS OMNI Life Science GmbH & Co. KG
11:15 - 11:30 C08 - Process- and cell specific biomimetic matrices enable culture of functional stem cells
Sandra Segeletz, denovoMATRIX GmbH
11:30 - 11:45 C09 - Development of novel tools and technologies for cardiovascular research
Dominik Eckardt, Miltenyi Biotec B.V. & Co. KG
11:45 - 12:00 C10 - Revolutionizing drug discovery for neurological disorders through precision medicine
Sandra Lubitz, Evotec SE
12:00 - 12:15 C11 - Why you should routinely test the genomic integrity of your cell lines
Agnes Miermont, Stem Genomics
11:00 - 12:30
Bronze Supporter II
(Chairs: Michael Rieger / Claudia Waskow)
11:00 - 11:15 C12 - Why you should give a HEK: advantages of human derived cytokines and growth factors
Rebecca Northeast, Proteintech Group
11:15 - 11:30 C13 - 3D stem cell culture: use of mixed reality to support your learning
Tim Wessel, Thermo Fisher Scientific
11:30 - 11:45 C14 - Functional connectivity of sympathetic neurons with cardiomyocytes in a human iPSC-derived innervated cardiac muscle model
Maria-Patapia Zafeiriou, University Medical Center Göttingen for Peprotech GmbH
11:45 - 12:00 C15 - A new method for the automated enumeration and analysis of CD34+ hematopoietic stem and progenitor cells by flow cytometry
Andreas Böhmler, Beckman Coulter GmbH
12:00 - 12:15 C16 - Industrialized CRISPR iPS cells enable Alzheimer’s disease modeling effort at scale for NIH’s iNDI Project
Kai Wilkens, Synthego
12:30 - 14:00 Lunch break / Industry exhibition               supported by Beckman Coulter​
13:00 - 14:00 Meet-the-expert tables (limited to 10 participants each, registration is possible at the registration desk)
Simon Haas, Ulrich Martin
14:00 - 16:15
Presidential Symposium
Chairs: Oliver Brüstle / Hans Schöler
14:00 - 14:45 Presidential Invite
& EMBO Keynote Lecture
PS1 - Recent progress in iPS cell research and application
Shinya Yamanaka, Center for iPS Cell Research and Application (CiRA), Kyoto, Japan, EMBO Associate Member
14:45 - 15:15 GSCN 2022 Young Investigator Award
PS2 - Single-cell systems understanding of the hematopoietic stem cell system in health and disease
Simon Haas, Max Delbrück Center/BIMSB & BIH, Berlin
15:15 - 15:45 GSCN 2022 Hilde Mangold Award
& EMBO YIP Lecture
PS3 - Liver organoids to study regeneration and cancer across biological scales
Meritxell Huch, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
15:45 - 16:15 GSCN Publication of the Year 2021 - 2022 Award
PS4 - Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity
Fatma Uzbas, Helmholtz Zentrum Munich
16:15 - 16:30 Break time / Industry exhibition
16:30 - 18:30

Poster session II (P092 - P179, X02 - X05)                      supported by Miltenyi​
(with beverages)
Stem cells in disease modeling & drug development: P092 - P144
Stem cells in aging & disease: P145 - P157
Hematopoietic stem cells: P158 - P171
Computational stem cell biology & systems biology: P172 - P179

Even numbers: 16:30 - 17:30
Odd number: 17:30 - 18:30

19:30 - 01:00

GSCN networking event for all participants
The entrance fee is collected on site
Event location:  
 Heaven Münster
Am Hawerkamp 29a, 48155 Münster



Friday, 16 September 2022

09:00 - 10:30 Concurrent scientific working group session III  
09:00 - 10:30
Stem cell in disease modeling & drug development II
(Chairs: Julian Grünewald / Karl-Ludwig Laugwitz)                supported by Molecular Devices​
09:00 - 09:30 T31 - Engineered CRISPR prime editors with compact, untethered reverse transcriptases
Julian Grünewald, Klinikum rechts der Isar, TU Munich
09:30 - 09:45 T32 - LZTR1 oligomerization drives Noonan syndrome-linked cardiac pathology in patient-derived and CRISPR-corrected iPSCs
Alexandra Busley, University Medical Center, Göttingen
09:45 - 10:00 T33 - Evaluation of potential therapeutic approaches for PPCS deficiency-associated dilated cardiomyopathy in patient iPSC models
Sarah Kübler, Klinikum rechts der Isar, TU Munich
10:00 - 10:15 T34 - Insights into the pathophysiology of Aicardi-Goutières syndrome implementing CRISPR/Cas9-engineered iPSCs as an experimental model
Nina Hein-Fuchs, Paul Ehrlich Institute, Langen
10:15 - 10:30 T35 - Modeling Langerhans cell histiocytosis using induced pluripotent stem cells
Giulio Abagnale, Children’s Cancer Research Institute, Vienna, Austria
09:00 - 10:30
Pluripotency & reprograming
(Chairs: Ivan Bedzhov / Micha Drukker)
09:00 - 09:30 T36 - In vitro generation of germ cells: implications for fertility and healthy longevity
Vittorio Sebastiano, University of Stanford, CA, USA
09:30 - 09:45 T37 - Enhancing Sox/Oct cooperativity delivers high-grade developmental reset
Sergiy Velychko, MPI for Molecular Biomedicine, Münster
09:45 - 10:00 T38 - Skeletal muscle organoids recapitulate fetal myogenesis  and provide a system to model Duchenne muscular dystrophy
Holm Zaehres, Ruhr University, Bochum
10:00 - 10:15 T39 - Pre-mRNA splicing rules that program cardiac contractility
Deniz Bartsch, University Clinics Cologne
10:15 - 10:30 T40 - Uncovering a novel myogenic regulator that facilitates reprogramming of fibroblasts into functional myogenic progenitor cells
Giada Bacchin, Swiss Federal Institute of Technology (ETH) Zurich
09:00 - 10:30
Computational stem cell biology & systems biology
(Chairs: Georg Fuellen / Carsten Marr)
09:00 - 09:30 T41 - Predicting the future state of differentiating cells
Laleh Haghverdi, Max Delbrück Center, Berlin 
09:30 - 09:45 T42 - Mathematical modeling of chronic lymphocytic leukemia cell kinetics under therapy with Ibrutinib
Melanie Schulz, Helmholtz Zentrum Munich
09:45 - 10:00 T43- Expression kinetics of differentiating mouse embryonic stem cells
Fabian Titz-Teixeira, University Cologne
10:00 - 10:15 T44 - Lifetime dynamics of haematopoietic stem cell clones inferred from Polylox barcoding
Maurice Langhinrichs, DKFZ Heidelberg
10:15 - 10:30 T45 - Upon stem cell maturation, deregulation of epigenetic marks is correlated to differential exon usage of developmental genes
Volkhard Helms, Saarland University, Saarbrücken
10:30 - 11:00 Break time / Industry exhibition                       supported by denovoMATRIX  
11:00 - 12:30 Concurrent strategic working group session  
11:00 - 12:30
Clinical trials & regulatory affairs
(Chairs: Andreas Kurtz / Torsten Tonn)
11:00 - 11:30 S1 - Perspectives on the immunological assessment of autologous, homozygous, and hypoimmunogenic iPSCs
Micha Drukker, Leiden University
11:30 - 12:00 S2 - NK cells as carriers for chimeric antigen receptor (CAR) for targeted cancer immunotherapies
Torsten Tonn, TU Dresden, DRK Blood donor service North-East
12:00 - 12:30 S3 -The new Clinical Trials Regulation (EU) No 536/2014
Jan Paus, Ethics Committee of the Westphalia-Lippe Medical Association, Münster 
11:00 - 12:30
Career development
(Chairs: Marieke Essers / Karin Höhne)
11:00 - 11:45 S4 - Towards responsible research for bench scientists
Ulf Tölch, BIH Quest at Charité, Berlin
11:45 - 12:30 Panel discussion  
11:00 - 12:30
Technologies in stem cell research
(Chairs: Andreas Bosio / Sebastian Diecke)
11:00 - 11:30 S5 - Hematopoietic stem cell dynamics inferred from large-scale genomic sequencing data sets
Jamie Blundell, Hutchinson-MRC Research Center, Cambridge, UK
11:30 - 12:00 S6 - Measuring somatic mutations and consequences by single cell and single strand sequencing
Ashley Sanders, Max Delbrück Center (MDC-BIMSB), Berlin
12:00 - 12:30 S7 - The short and long story of sequencing for stem cell quality control
Franz-Josef Müller, University Clinics Schleswig-Hostein (UKSH), Kiel
12:30 - 14:00 Lunch break / Industry exhibition    supported by Thermo Fisher Scientific  
13:00- 14:00 Meet-the-expert-table (limited to 10 registered participants each, registration is possible at the registration desk)
Michaela Frye, Wolfgang Wagner
14:00 - 14:45
Keynote lecture IV & Pro-Scientia-Award ceremony
K4- Beta cell development and regeneration
Heiko Lickert, Helmholtz Zentrum München
Chair: Sara Wickström
Award ceremony: Rudolf Tauber, Eckhart-Buddecke-Stiftung
14:45 - 15:30
Keynote lecture V
K5 - Reconstitution of reproductive organs including germ cells using mouse pluripotent stem cells
Katsuhiko Hayashi, Kyushu University, Fukuoka, Japan
Chair: Ivan Bedzhov
15:30 - 15:50 Poster award ceremony
Daniel Besser
Poster awards                      supported by Eppendorf
Travel awards                       supported by STEMCELL Technologies
15:50 - 16:00 Closing remarks by the incoming GSCN president
Claudia Waskow 
  End of GSCN Conference 2022  
Keynote Speakers

Dieter Birnbacher (Düsseldorf, GER)

ELSA Keynote Speaker

Elena Cattaneo (Milan, IT)

Keynote Stem Cell Network NRW

Fiona Doetsch (Basel, CH)

Katsuhiko Hayashi
(Fukuoka, JAP)

Heiko Lickert 
(Munich, GER)

Pro-Scientia-Award | Eckhart-Buddecke-Stiftung

Hanna Mikkola (Los Angeles, US)

Shinya Yamanaka
 (Kyoto, JAP)
EMBO Associate Member

Speakers & Session Chairs

Sina Bartfeld (Berlin)
Ivan Bedzhov (Münster)
Daniel Besser (Berlin)
Andreas Bosio (Bergisch Gladbach)
Thomas Braun (Bad Nauheim)
Oliver Brüstle (Bonn)
German Camargo Ortega (Basel)
Tobias Cantz (Hannover)
Michael Cross (Leipzig)
Sebastian Diecke (Berlin)
Micha Drukker (Leiden, NL)
Marieke Essers (Heidelberg)
Hartmut Geiger (Ulm)
Ira Herrmann (Bonn)
Hannes Klump (Essen)
Andreas Kurtz (Berlin)
Nico Lachmann (Hannover)
Karl-Ludwig Laugwitz (Munich)
Carsten Marr (Munich)
Ulrich Martin (Hannover)  
Ana Martin-Villalba (Heidelberg)
Michael Rieger (Frankfurt a.M.)
Richard Schäfer (Frankfurt)
Insa Schröder (Darmstadt)
Hans Schöler (Münster)
Torsten Tonn (Dresden)
Andreas Trumpp (Heidelberg)
Wolfgang Wagner (Aachen)
Claudia Waskow (Jena)

email contact

Gold Supporters


Silver Supporters

Molecular Devices
StemCell Technologies

Bronze Supporters

Beckmann Coulter
Miltenyi Biotec
OLS Omni
Stem Genomics

Academic Supporters

Stem Cell Network.NRW